Allison M. Bradbury, PhD

Allison M. Bradbury, MS, PhD is a tenure track assistant professor in the Department of Pediatrics at The Ohio State University and Principal Investigator in the Center for Gene Therapy at Nationwide Children’s Hospital. She leads a R01-funded translational laboratory with the goal of improving the understanding of disease mechanisms resulting in rare pediatric neurologic disorders to develop safe and efficacious targeted gene therapy approaches.

Dr. Bradbury received her PhD in Biomedical Sciences from Auburn University (2009-2014) where her doctoral research was focused on the development of AAV gene therapy in a feline model of GM2 gangliosidosis. This therapy is now in human clinical trials. Successively, her postdoctoral research fellowship was completed at the University of Pennsylvania and supported by a NRSA F32 Fellowship and NIH K99/R00 Pathway to Independence grant. During her postdoctoral fellowship she demonstrated therapeutic efficacy in the canine model of globoid cell leukodystrophy (Krabbe disease) for the first time by utilizing AAV gene therapy to target both central and peripheral nervous system disease, with successful translation to the clinic. In her independent laboratory, Dr. Bradbury continues to optimize and translate next generation gene therapies for rare pediatric neurologic disorders.

Dr. Bradbury is also committed to training the next generation of promising basic and translational gene therapy researchers and strives for her laboratory to be an active and engaging environment for trainees to develop proficient laboratory and essential professional development skills. As such she currently mentors post-doctoral trainees, including as a Co-Sponsor on a NRSA F32, and a number of PhD students, including as a Sponsor on a NIH F99/K00 BRAIN Initiative Predoctoral to Postdoctoral Advancement in Neuroscience Award. Additionally, she has been selected for two consecutive years as a laboratory for the Simons Foundation Undergraduate Research Fellowship in Neuroscience Program; serves on numerous graduate committees; and serves on the Graduate Studies Committee for the Molecular, Cellular, and Developmental Biology Graduate Program at The Ohio State University.

Dr. Bradbury is passionate about the national interests surrounding rare diseases. She served a two-year term (2023-2025) as the Chair of the Patient Outreach Committee for the American Society of Gene and Cell Therapy. She also serves on the Scientific Advisory Board for two of the country’s most established rare disease societies, The National Tay-Sachs and Allied Diseases Association and the National MPS Society, as well as several smaller foundations.