Insight Series

Friend or Foe? Interplay Between Innate Immune Responses and Non-viral Gene Delivery

October 20, 2023 | 11:00 AM CT

This session will illustrate recent advances in our understanding of how pathogen recognition and consequent innate immune signaling may impact non-viral delivery of nucleic acids for better or for worse. 


  • Moderators: Federico Mingozzi, PhD - Spark Therapeutics, and Stefan Radtke, PhD - Fred Hutchinson Cancer Research Center

  • Kate Fitzgerald, PhD - University of Massachusetts Chan Medical School
    Toll-Like receptor signaling, innate nucleic acid sensors, and the innate immune response

  • Marina Dobrovolskaia, PhD - Frederick National Laboratory for Cancer Research
    Immunological Properties of LNPs & Nucleic Acid-Based APIs

  • Pedro Cejas, PhD - Spark Therapeutics
    Overcoming barriers to safe and efficient non-viral delivery of DNA

Watch on demand

More ASGCT Insights

Register for more sessions during ASGCT Insights Week, Oct. 16-20. Members and registrants can watch on demand!


Register for the ASGCT Policy Summit

September 23-24, 2024 | Washington, D.C.

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