Renata M. Stripecke, PhD
Hannover Medical School
What is your current professional status?
Head of the Lymphatic Cell Therapy Laboratory from the Excellence Cluster REBIRTH
What is your work setting (i.e. academic institution, government organization (i.e. FDA, NIH, etc.), bio-industry/pharmaceutical company, etc.)
What is your scientific area of research?
Hematology, Cancer, Chronic Infections, Immunology.
Why do you want to be a mentor?
I have supervised post-docs, pre-docs, master students and medical students and I enjoy doing it. My teaching activities in our international PhD programs focus on immunology and recombinant vector Systems, which are also main topics of research. I would like to contribute to “new minds” growing in science. In addition, scientific careers are sometimes not “linear”, and everyone experience some bumps here and there. It was very important for me to have mentors to give me perspectives regarding what was important to reach my academic goals along with a balanced life.
As a mentor, what are you hoping to gain from this experience?
Networking with PhD students and post-docs in my field for collaborations and maybe recruitments. Internationalization, scientific mobility and career development are important academic topics, which I support. It is great to keep in touch with the academic generations of the future!
How important are the following in the selection of a mentee: (1 – 5 scale, 1 = most important, 5 = least important)
a. Compatibility of Scientific Specialties - 1
b. Geographic Location - 2
c. Professional Status / Success - 2
d. Compatibility of Career Path - 1
e. Communication Style - 1
Summarized in a brief paragraph (150 words or less), please provide a biography that describes who you are and what you do in the field of gene and/or cell therapy.
I am quite cosmopolitan, as I was born and grew up in Brazil, where I got my BS and MS in Genetics (UNICAMP), then moved to Germany for my PhD in molecular biology (EMBL), then to the US for postdoctoral training and assistant professor positions in gene and immune therapy (USC, UCLA), and finally as an associate professor to Germany (MHH). My expertise is on reprogramming cells of the immune system using recombinant vectors in order to accelerate the immune reconstitution after cancer, transplantation or infections. My main focus is on dendritic cells, due to their central role in orchestration of adaptive cellular and humoral responses. My group developed new technologies to genetically reprogram DC precursors that differentiate into potent DCs. We have expertise with multicistronic lentiviral vectors expressing combinations of cytokines and antigens. This technology was adapted to GMP-compliant production of "individualized" gene modified cell vaccine for future clinical use (accelerated immune reconstitution after stem cell transplantation). We are developing new modalities of humanized mice to study hematopoietic stem cell transplantation, cancer development and viral infections.
Click here to view Renata Stripecke's CV.