Co-Chairs
Douglas J. Jolly, PhD
Thomas Tillett

Speakers
William W. Li, MD
Gene Transfer of FGF1 for Critical Limb Ischemia: A Phase III Clinical Trial

Robert Sims, MD
Progress in the Development of Sipuleucel-T for the Treatment of Men with Metastatic, Castrate Resistant Prostate Cancer

Prannath Marrott, MD
Development of HGF Gene Therapy Product (Collategene) for Critical Limb Ischemia

Sander van Deventer, MD, PhD
Glybera for Lipoprotein Lipase Deficiency

Note: No CME Credit will be given for this session.

Chair
Ernst Wagner, PhD

Speakers
Lonnie D. Shea, PhD
Localized Gene Delivery by Biomaterial Immobilization

Aliasger K. Salem, PhD
Pulsatile Release of Biomolecules from Polydimethylsiloxane

David M. Lynn, PhD
A 'Multilayered' Approach to the Delivery of DNA: Exploiting the Structure of Polyelectrolyte Multilayers to Promote Surface-Mediated Transfection and Tunable Multi-Agent Delivery

Daniel G. Anderson, PhD
Combinatorial Development of Biomaterials for Gene Delivery

Chair
Jacqueline Corrigan-Curay, MD, JD

Speakers
Daniel M. Takefman, PhD
Gene Modified Cell Based Therapies:  FDA Perspectives

Joy Cavagnaro, PhD, DABT, RAC
Limitations of Preclinical Studies for Predicting Safety of Uniquely Human Specific Therapies

Carl H. June, MD
Prolonged Engraftment and Decade Long Safety Record of Engineered T Cells

Panel Discussion
Helen E. Heslop, MD
Michel Sadelain, MD, PhD
Steven A. Rosenberg, MD, PhD

Chair
David B. Weiner, PhD

Speakers
Valder Arruda, MD, PhD
Gene Therapy for Tolerance Induction in Large Animal Models

Yiping Yang, MD, PhD
Innate Immunity in AAV-mediated Gene Therapy

David B. Weiner, PhD
High Immune Potency of Highly Optimized EP DNA Vaccines in Animal Models and Humans

Michael T. Lotze, MD
MicroRNAs in Immune Regulation-Opportunities for Cancer Gene Therapy

Chair
Maria G. Castro, PhD

Speakers
Anna M. Krichevsky, PhD
MicroRNAs as Targets for Glioma Therapy

M. Maral Mouradian, MD
MicroRNAs in Parkinson's Disease and Other Neurodegenerative Disorders

Sean E. Lawler, PhD
MicroRNA Alterations and Functions in Glioblastoma

Al Charest, PhD
Nanoparticle-Mediated Delivery of siRNA in a Pre-Clinical Mouse Model of Glioblastoma Multiforme

Chair
Philip D. Gregory, PhD

Speakers
Matthew Hirsch, PhD
The AAV Induced DNA Damage Response in Human Pluripotent Cells

Philip D. Gregory, PhD
Stem Cell Modification with Zinc Finger Nucleases

Frederic Paques, PhD
Meganucleases and Viral Vectors: Alternative or Complementary Approaches

Andrew M. Scharenberg, MD
Gene Editing Using Lentiviral Expression of Homing Endonucleases

Speakers
James Ellis, PhD
Carolyn Lutzko, PhD

Speakers
Mark A. Kay, MD, PhD
Luigi M. Naldini, MD, PhD