8:00 am to 10:00 am
10:00 am to 10:30 am
10:30 am to 12:30 pm
Chair
John J. Nemunaitis, MD
Speaker
John J. Nemunaitis, MD
Success of Gene Therapy - A Personalized and Personal Approach
Lilia Bi, PhD
Recovery and Reduction Costs for Cell-based Gene Therapy Products
Carl H. June, MD
Genetically Engineered T Cells: Can We Afford Not To Do This?
Jeffrey Schlom, PhD
Recombinant Cancer Vaccines as Monotherapy and in Combination Therapy
10:30 am to 12:30 pm
Chair
Evan Y. Snyder, MD, PhD, FAAP
Speakers
Inder Verma, PhD
Cancer Stem Cells: Lessons from Glioblastomas
Roger J. Packer, MD
Childhood Brain Tumors: Opportunities for Biologic-Based Therapies
Evan Y. Snyder, MD, PhD, FAAP
"Lineage Mapping" The Development of a Brain Tumor
Carl Bart Rountree, MD
The Role of Stem Cells and Cancer Stem Cells in Liver Cancer
10:30 am to 12:30 pm
Chair
Stephen Gottschalk, MD
Speakers
Si-Yi Chen, MD, PhD
DC-based Tumor Vaccine by Combining SOCS1 Silencing and TLR Signaling
Michael A. Barry, PhD
Gene-based Vaccines Against Mucosal Pathogens
Sattva S. Neelapu, MD
Targeting Chemokine Receptors with Fusion DNA Vaccines
Stephen Gottschalk, MD
Adenoviral Vaccines for Enhancing T-cell Therapies for Cancer
10:30 am to 12:30 pm
Chair
Dieter C. Gruenert, PhD
Speakers
Peter M. Glazer, MD, PhD
Targeted Gene Modification in Hematopoietic Stem Cells via Triple Helix Formation
Linzhao Cheng, PhD
Gene Targeting in Human Pluripotent Stem Cells
Dieter C. Gruenert, PhD
Modification of the CF and Sickle Cell Anemia iPS cells by SFHR
Robert Blelloch, MD, PhD
MicroRNA Regulation of Embryonic Stem Cell Self-Renewal and Differentiation
10:30 am to 12:30 pm
Chair
Shulin Li, PhD
Speakers
Christian Plank, PhD
Nanomagnetic Nucleic Acid Delivery
Declan M. Soden, PhD
Endoscopic Electroporation: Targeted Gene Delivery to Intraluminal Tissues
Kate E. Broderick, PhD
Dermal Electroporation Devices for Prophylactic DNA Vaccine Delivery
Laurence JN Cooper, MD, PhD
Non-viral Gene Transfer into Human T Cells
10:30 am to 12:30 pm
Chair
Frederic D. Bushman, PhD
Speakers
Christof von Kalle, MD
The Clonal Distribution of Insertion Site Repertoires
Matthew H. Porteus, MD, PhD
Gene Targeting with Zinc Finger Nucleases in Primary Cells
Frederic D. Bushman, PhD
HIV DNA Integration: Mechanism and Consequences
Ko Mitani, PhD
Chromosomal Manipulation of Human Pluripotent Stem Cells using Adenoviral Vectors
12:30 pm to 2:00 pm
2:00 pm to 4:00 pm
4:00 pm to 4:30 pm
4:30 pm to 6:30 pm
Chair
Kenneth Cornetta, MD
Speakers
John J. Rossi, PhD, introduces
Katherine A. High, MD
Outstanding Achievement Award Lecture
Jean Bennett, MD, PhD
An Aye for Gene Therapy: Lessons from a Clinical Trial for Congenital Blindness
David A. Williams, MD
New Approaches to Gene Therapy for Fanconi Anemia
6:30 pm to 8:30 pm
7:00 pm to 10:00 pm
Chair
Fabio Candotti, MD
Speakers:
Mary C. Dinauer, MD, PhD
Gene Therapy for CGD - from Basic Discoveries to the Start of Clinical Trials
Alessandro Aiuti, MD, PhD
Conditioning Regimens for Haematopoietic Gene Therapy
Harry Malech, MD
Update on Gene Therapy Trials for CGD - the USA Perspective
Manual Grez, PhD
The European Experience on Gene Therapy for CGD
Adrian Thrasher, MD, PhD
Update on Clinical Trials for XC1-SCID, ADA and ALD
Toni Cathomen, PhD
Zinc-Finger Approaches to Gene Therapy
Linzhao Cheng, PhD
The Potential of iPS Cells in Understanding and Treating Genetic Disorders
This symposium is supported by:
