Outstanding New Investigator Symposium 200
8:00 am – 9:45 am
Co-Chairs
David M. Bodine, PhD
Donald B. Kohn, MD
Speakers
Renier Brentjens, MD, PhD
Treatment of B-cell Malignancies with CD19 Targeted T-cells
Barbara Savoldo, MD
Improving T Cell Based Therapies
Tatiana Segura, PhD
Gene Delivery In Three Dimensions
Break
9:45 am – 10:00 am
Scientific Symposium 210
10:00 am - 12:00 pm
Cancer Cell Therapy
Chair
Laurence JN Cooper, MD, PhD
Speakers
David M. Spencer, PhD
Genetically Enhanced Dendritic Cell Immunotherapy for Cancer
Bruce R. Blazar, MD
T-regulatory Cells in the Clinic
Richard A. Morgan, PhD
Gene Therapy Using Highly Avid T Cell Receptors Breaks
Tolerance and Elicits Cancer Regression
Frank Marini, PhD
Mesenchymal Stem Cells: Tumor Associated Fibroblasts and
Potent Gene Delivery Vehicles
Scientific Symposium 211
10:00 am - 12:00 pm
Understanding and Manipulating Stem Cell Behavior
Chair
Jan A. Nolta, PhD
Speakers
Frederick Levine, MD, PhD
Development of Human Pancreatic Beta-Cell Lines: Application to
High-Throughput Screening
Paul Knoepfler, PhD
Myc Directs Stem Cell Pluripotency, Self-Renewal and
Tumorigenicity
Jeanne F. Loring, PhD
The Secret Lives of Stem Cells: How Molecular Networks Control
Pluripotence
Mark Mercola, PhD
Small Molecules to Direct Cardiomyocyte Differentiation from
Stem Cells
Scientific Symposium 212
10:00 am - 12:00 pm
Progress in Genetic Vaccination Technologies
Chair
David B. Weiner, PhD
Speakers
Iacob Mathiesen, PhD
Immune Therapy by Electroporation
George Coukos, MD, PhD
Immune-Gene Therapy Targeting the Tumor Vasculature
Hildegund CJ Ertl, MD
HIV-1 Vaccines Based on Adenoviral Vectors
Alain Rolland, PharmD, PhD
Development of Vaxfectin-Adjuvanted Pandemic Influenza DNA
Vaccines
Scientific Symposium 213
10:00 am - 12:00 pm
Antagomirs
Chair
Bruce Sullenger, PhD
Speakers
Peter Linsley, PhD
Therapeutic Targeting of Micro RNAs
C. Frank Bennett, PhD
Treatment of Neurodegenerative Diseases with Antisense Oligonucleotides
and
Small RNA Regulation of Transcription
Kevin V. Morris, PhD
Non-Coding RNAs Direct Epigenetic Regulation of Transcription in Human Cells
Xuan Yue, PhD
Regulation of Transcription by Small RNAs Complementary to Sequences Downstream from the 3' Termini of Genes
Scientific Symposium 214
10:00 am - 12:00 pm
Lung Immunology Relevant to Gene Transfer
Co-Chairs
Paul B. McCray, Jr., MD
Uta Griesenbach, PhD
Speakers
Neil R. Hackett, PhD
Innate Immune Response of Airway to Viral Gene Transfer
Alistair Ramsay, PhD
T Cell Responses to Transgenes and Vectors Delivered in the
Lung
Erik Falck-Pedersen, PhD
Antigen Presenting Cell Recognition of rAdenovirus: interferon-stimulating
DNA
Maria Limberis, PhD
Viral Gene Transfer to the Lung: Immune Implications
Scientific Symposium 215
10:00 am - 12:00 pm
How Viruses Work: New Insights in Basic Virology
Co-Chairs
Guangping Gao, PhD
Stephen J. Russell, MD, PhD
Speakers
Renate Koenig, PhD
Global Analysis of Host-Pathogen Interactions Using Systems
Biology
Arun Srivastava, PhD
Role of Tyrosine-Phosphorylation in the Life Cycle of AAV Vectors
Matthew D. Weitzman, PhD
Interactions between Viruses and the Cellular DNA Damage Machinery
Andrew H. Baker, PhD
Assessing Adenovirus Interactions with Blood Coagulation Factors
Lunch Break
12:00 pm – 1:45 pm
Meet-the-Investigator 220
12:15 pm - 1:30 pm
Meet-the-Investigator Lunch
Speakers
Michele P. Calos, PhD & John J. Rossi, PhD
New Nucleic Acid Technologies
Meet-the-Investigator 221
12:15 pm - 1:30 pm
Meet-the-Investigator Lunch
Speakers
Harry L. Malech, MD & Derek A. Persons, MD, PhD
Gene Therapy for Hematologic Disorders
Meet-the-Investigator 222
12:15 pm - 1:30 pm
Meet-the-Investigator Lunch
Speakers
David M. Bodine, PhD & Punam Malik, MD
Barrier and Insulator Elements for Gene Therapy Vectors
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George Stamatoyannopoulos Lecture 230
1:45 pm - 3:00 pm
George Stamatoyannopoulos Lecture
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Chair
Kenneth G. Cornetta, MD
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Speaker
Brian J. Druker, MD
Imatinib as a Paradigm of Molecularly
Targeted Cancer Therapies
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Simultaneous Oral Abstract Sessions 240
3:15 pm – 5:15 pm
Exhibit Hall Welcome Reception and Poster Presentation Session 1
5:30 pm – 8:30 pm