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ASGT Busines Meeting (with continental breakfast)
7:30 am – 8:00 am

Scientific Symposium 400
8:15 am - 10:15 am
Cell Therapy in CV Disease: Clinical & Preclinical Studies

Chair
Matthew L. Springer, PhD

Speaker
Matthew L. Springer, PhD
Bone Marrow Cell Therapy for Cardiac Disease: Impact of Donor Age and Infarction

Douglas Losordo, MD
Autologous CD34 Cell Therapy for Refractory Angina

Michael P. Murphy, MD
A Phase I/II Analysis of Autologous Bone Marrow Cells to Promote Limb Salvage in Patients with Critical Limb Ischemia

Satellite Presentation 400
9:45 am - 10:15 am
NHLBI Gene Therapy Resource Program

Scientific Symposium 401
8:15 am - 10:15 am
Coupling Imaging with Chemical Gene Therapy Methods

Chair
Francis C. Szoka, Jr., PhD

Speakers
Theresa M. Reineke, PhD
Illuminating the Mechanism of Glycopolymer-Mediated DNA Delivery

Kevin G. Rice, PhD
Application of Quantitative Bioluminescence Imaging to measure Polyplex Mediated Gene Expression and RNAi Mediated Knockdown

Suzie H. Pun, PhD
Trafficking of Polymeric Gene Carriers

Rudolph L. Juliano, PhD
Receptor Targeted Delivery of Antisense and siRNA Oligonucleotides

Scientific Symposium 402
8:15 am - 10:15 am
Improved Genetic Engineering Methods for Induced Pluripotent Stem Cell Technologies

Chair
Gay Crooks, MD

Speakers
Gustavo Mostoslavsky, MD, PhD
iPS Cell Generation Using a Single Lentiviral Stem Cell Cassette

Tim Townes, PhD
Induced Pluripotent Stem (iPS) Cells and Gene Replacement Therapy for Sickle Cell Disease

Sheng Ding, PhD
A Chemical Approach to Stem Cell Fate Regulation

Ronald G. Crystal, MD
Genetic Control of Wayward Pluripotent Stem Cells and Their Progeny after Transplantation

Scientific Symposium 403
8:15 am - 10:15 am
Gene and Cell Therapy for Brain Injury

Chair
Nicole Deglon, PhD

Speakers
K. Amy Chen, PhD
Stem Cells, Gene Therapy, and Regenerative Medicine for Neurological Disorders

Deborah J. Watson, PhD
Targeting Vector and Cell-Based Therapies to Areas of CNS Damage

Karen S. Aboody, MD
Neural Stem Cell Mediated Tumor-Selective Gene Delivery: Towards Clinical Trials

Matthias Stadtfeld, PhD
Generation and Therapeutic Potential of Induced Pluripotent Stem Cells

Scientific Symposium 404
8:15 am - 10:15 am
Modulation of Immune Response to Transplanted Cells

Chair
Maria Grazia Roncarolo, MD, PhD

Speakers
Katherine A. High, MD
Immune Responses to Vector and Transgene Product in AAV-mediated Gene Transfer

David Klatzmann, MD, PhD
Of Transplantation, Tolerance and Regulatory T Cells

Jonathan Bramson, PhD
Dendritic Cell Vaccines for Cancer Immunotherapy

Soosan Ghazizadeh, PhD
Characterization and Modulation of Immune Responses to the Transplantation of Genetically Modified Autologous Skin Cells

Scientific Symposium 405
8:15 am - 10:15 am
Clinical Trials

Chair
Barrie J. Carter, PhD

Speakers
R. Jude Samulski, PhD
Designing AAV Vectors for Clinical Trials

Geoff Symonds, PhD
Phase II Clinical Trial Results: Gene Therapy for HIV

Bruce Sullenger, PhD
Translating Aptamer-Anecdote Pairs into the Clinic

Sunyoung Kim, D.Phil
Enhanced Angiogenesis by Two Isoforms of HGF Expressed from Naked DNA: Data from Phase I Human Trials for Coronary Artery Disease and Critical Limb Ischemia

Break
10:15 am – 10:45 am

Simultaneous Oral Abstract Sessions 410
10:45 am – 12:45 pm

Lunch Break
12:45 pm – 2:30 pm

Meet-the-Investigator 420
1:00 pm - 2:15 pm
Meet-the-Investigator Lunch

Speakers
Katherine A. High, MD & John T. Gray, PhD
Gene Therapy for Hemophilia

Meet-the-Investigator 421
1:00 pm - 2:15 pm
Meet-the-Investigator Lunch

Speakers
Adrian J. Thrasher, MD, PhD & Jean Bennett, MD, PhD
Gene Therapy of the Eye

Presidential Symposium 430 2:30 pm - 5:00 pm Presidential Symposium
Chair David M. Bodine, PhD

Speakers
John Carpten, PhD Interrogation of Cancer Genomes: Towards More Profile-based Therapeutic Decision Making	John J. Nemunaitis, MD Personalized Cancer Gene Therapy
Helen E. Heslop, MD Immunotherapy of Viral Infections and Malignancy	Chiara Bonini, MD T-cell Based Gene Therapy to Improve Hematopoietic Stem Cell Transplantation

Poster Presentation Session III
5:15 pm – 7:00 pm

Saturday Night Party on the Terrace – Live Music!
7:00 pm – 11:00 pm
Featuring live music by CoolBandLuke

Jointly sponsored by:

Beckman Research Institute at City of Hope

Gene Therapeutics Research Institute at Cedars-Sinai

Program in Gene Therapy
Program in Stem Cell Transplantation